furosemide injection, USP ANSYR Adverse Reactions

ADVERSE REACTIONS

Adverse reactions are categorized below by organ system and listed by decreasing severity.

Gastrointestinal System Reactions
1.
Hepatic encephalopathy in patients with hepatocellular insufficiency
2.
Pancreatitis
3.
Jaundice (intrahepatic cholestatic jaundice)
4.
Increased liver enzymes
5.
Anorexia
6.
Oral and gastric irritation
7.
Cramping
8.
Diarrhea
9.
Constipation
10.
Nausea
11.
Vomiting
Systemic Hypersensitivity Reactions
1.
Severe anaphylactic or anaphylactoid reactions (e.g. with shock)
2.
Systemic vasculititis
3.
Interstitial nephritis
4.
Necrotizing angiitis
Central Nervous System Reactions
1.
Tinnitus and hearing loss
2.
Paresthesias
3.
Vertigo
4.
Dizziness
5.
Headache
6.
Blurred Vision
7.
Xanthopsia
Hematologic Reactions
1.
Aplastic anemia
2.
Thrombocytopenia
3.
Agranulocytosis
4.
Hemolytic anemia
5.
Leukopenia
6.
Anemia
7.
Eosinophilia
Dermatologic-Hypersensitivity Reactions
1.
Exfoliative dermatitis
2.
Bullous pemphigoid
3.
Erythema multiforme
4.
Purpura
5.
Photosensitivity
6.
Urticaria
7.
Rash
8.
Pruritus
9.
Stevens-Johnson Syndrome
10.
Toxic epidermal necrolysis
Cardiovascular Reactions
1.
Orthostatic hypotension may occur and be aggravated by alcohol, barbiturates or narcotics
2.
Increase in cholesterol and triglyceride serum levels
Other Reactions
1.
Hyperglycemia
2.
Glycosuria
3.
Hyperuricemia
4.
Muscle spasms
5.
Weakness
6.
Restlessness
7.
Urinary bladder spasm
8.
Thrombophlebitis
9.
Transient injection site pain following intramuscular injection
10.
Fever

Whenever adverse reactions are moderate or severe, furosemide dosage should be reduced or therapy withdrawn.

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Adverse Reactions

ADVERSE REACTIONS

Adverse reactions are categorized below by organ system and listed by decreasing severity.

Gastrointestinal System Reactions
1.
Hepatic encephalopathy in patients with hepatocellular insufficiency
2.
Pancreatitis
3.
Jaundice (intrahepatic cholestatic jaundice)
4.
Increased liver enzymes
5.
Anorexia
6.
Oral and gastric irritation
7.
Cramping
8.
Diarrhea
9.
Constipation
10.
Nausea
11.
Vomiting
Systemic Hypersensitivity Reactions
1.
Severe anaphylactic or anaphylactoid reactions (e.g. with shock)
2.
Systemic vasculititis
3.
Interstitial nephritis
4.
Necrotizing angiitis
Central Nervous System Reactions
1.
Tinnitus and hearing loss
2.
Paresthesias
3.
Vertigo
4.
Dizziness
5.
Headache
6.
Blurred Vision
7.
Xanthopsia
Hematologic Reactions
1.
Aplastic anemia
2.
Thrombocytopenia
3.
Agranulocytosis
4.
Hemolytic anemia
5.
Leukopenia
6.
Anemia
7.
Eosinophilia
Dermatologic-Hypersensitivity Reactions
1.
Exfoliative dermatitis
2.
Bullous pemphigoid
3.
Erythema multiforme
4.
Purpura
5.
Photosensitivity
6.
Urticaria
7.
Rash
8.
Pruritus
9.
Stevens-Johnson Syndrome
10.
Toxic epidermal necrolysis
Cardiovascular Reactions
1.
Orthostatic hypotension may occur and be aggravated by alcohol, barbiturates or narcotics
2.
Increase in cholesterol and triglyceride serum levels
Other Reactions
1.
Hyperglycemia
2.
Glycosuria
3.
Hyperuricemia
4.
Muscle spasms
5.
Weakness
6.
Restlessness
7.
Urinary bladder spasm
8.
Thrombophlebitis
9.
Transient injection site pain following intramuscular injection
10.
Fever

Whenever adverse reactions are moderate or severe, furosemide dosage should be reduced or therapy withdrawn.

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