Methotrexate Vial What is Methotrexate Injection?

What is Methotrexate Injection?

Methotrexate Injection is a prescription medicine used: in adults and children:
•
in combination with other chemotherapy medicines to treat acute lymphoblastic leukemia (ALL) to help prevent (prophylaxis) and to treat leukemia that spreads to the covering of the brain and spinal cord (meninges).
•
to treat non-Hodgkin lymphoma
•
in combination with other chemotherapy medicines to treat osteosarcoma

in adults:

•
in combination with other chemotherapy medicines to treat breast cancer
•
alone to treat squamous cell carcinoma of the head and neck
•
in combination with other chemotherapy medicines to treat gestational trophoblastic neoplasia
•
in adults to treat rheumatoid arthritis (RA)
•
in children to treat polyarticular juvenile idiopathic arthritis (pJIA)
•
in adults to treat severe psoriasis

Do not receive Methotrexate Injection if you:

•
have had a severe allergic reaction to Methotrexate Injection. See "What is the most important information I should know about Methotrexate Injection?"
•
you are pregnant and are being treated, or will be treated with Methotrexate Injection for rheumatoid arthritis, pJIA, or severe psoriasis, or for any disease other than cancer. Methotrexate Injection can cause harm to an unborn baby including birth defects or death of an unborn baby. See "What is the most important information I should know about Methotrexate Injection?”

Before you receive Methotrexate Injection, tell your healthcare provider about all of your medical conditions, including if you:

•
have kidney problems or are receiving dialysis treatments
•
have liver problems
•
have a history of neurologic problems, including seizures
•
drink-alcohol containing beverages during treatment with Methotrexate Injection, or if there are any changes in the amount of alcoholic beverages you drink
•
have fluid in your stomach-area (ascites)
•
have lung problems or fluid in your lungs (pleural effusion)
•
plan to have any surgeries with general anesthesia, including dental surgery
•
have stomach ulcers (peptic ulcer disease)
•
have ulcerative colitis
•
have recently received or are scheduled to receive a vaccine. You should not receive live vaccines during treatment with Methotrexate Injection.
•
are breastfeeding or plan to breastfeed. Methotrexate may pass into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of Methotrexate Injection.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking certain medicines can affect the amount of methotrexate in your blood and can increase your risk for serious side effects.

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Find Methotrexate Vial medical information:

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Health Professional Information

What is Methotrexate Injection?

What is Methotrexate Injection?

Methotrexate Injection is a prescription medicine used: in adults and children:
•
in combination with other chemotherapy medicines to treat acute lymphoblastic leukemia (ALL) to help prevent (prophylaxis) and to treat leukemia that spreads to the covering of the brain and spinal cord (meninges).
•
to treat non-Hodgkin lymphoma
•
in combination with other chemotherapy medicines to treat osteosarcoma

in adults:

•
in combination with other chemotherapy medicines to treat breast cancer
•
alone to treat squamous cell carcinoma of the head and neck
•
in combination with other chemotherapy medicines to treat gestational trophoblastic neoplasia
•
in adults to treat rheumatoid arthritis (RA)
•
in children to treat polyarticular juvenile idiopathic arthritis (pJIA)
•
in adults to treat severe psoriasis

Do not receive Methotrexate Injection if you:

•
have had a severe allergic reaction to Methotrexate Injection. See "What is the most important information I should know about Methotrexate Injection?"
•
you are pregnant and are being treated, or will be treated with Methotrexate Injection for rheumatoid arthritis, pJIA, or severe psoriasis, or for any disease other than cancer. Methotrexate Injection can cause harm to an unborn baby including birth defects or death of an unborn baby. See "What is the most important information I should know about Methotrexate Injection?”

Before you receive Methotrexate Injection, tell your healthcare provider about all of your medical conditions, including if you:

•
have kidney problems or are receiving dialysis treatments
•
have liver problems
•
have a history of neurologic problems, including seizures
•
drink-alcohol containing beverages during treatment with Methotrexate Injection, or if there are any changes in the amount of alcoholic beverages you drink
•
have fluid in your stomach-area (ascites)
•
have lung problems or fluid in your lungs (pleural effusion)
•
plan to have any surgeries with general anesthesia, including dental surgery
•
have stomach ulcers (peptic ulcer disease)
•
have ulcerative colitis
•
have recently received or are scheduled to receive a vaccine. You should not receive live vaccines during treatment with Methotrexate Injection.
•
are breastfeeding or plan to breastfeed. Methotrexate may pass into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of Methotrexate Injection.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking certain medicines can affect the amount of methotrexate in your blood and can increase your risk for serious side effects.
Prescribing Information
Download Prescribing Information

Health Professional Information

What is Methotrexate Injection?

What is Methotrexate Injection?

Methotrexate Injection is a prescription medicine used: in adults and children:
•
in combination with other chemotherapy medicines to treat acute lymphoblastic leukemia (ALL) to help prevent (prophylaxis) and to treat leukemia that spreads to the covering of the brain and spinal cord (meninges).
•
to treat non-Hodgkin lymphoma
•
in combination with other chemotherapy medicines to treat osteosarcoma

in adults:

•
in combination with other chemotherapy medicines to treat breast cancer
•
alone to treat squamous cell carcinoma of the head and neck
•
in combination with other chemotherapy medicines to treat gestational trophoblastic neoplasia
•
in adults to treat rheumatoid arthritis (RA)
•
in children to treat polyarticular juvenile idiopathic arthritis (pJIA)
•
in adults to treat severe psoriasis

Do not receive Methotrexate Injection if you:

•
have had a severe allergic reaction to Methotrexate Injection. See "What is the most important information I should know about Methotrexate Injection?"
•
you are pregnant and are being treated, or will be treated with Methotrexate Injection for rheumatoid arthritis, pJIA, or severe psoriasis, or for any disease other than cancer. Methotrexate Injection can cause harm to an unborn baby including birth defects or death of an unborn baby. See "What is the most important information I should know about Methotrexate Injection?”

Before you receive Methotrexate Injection, tell your healthcare provider about all of your medical conditions, including if you:

•
have kidney problems or are receiving dialysis treatments
•
have liver problems
•
have a history of neurologic problems, including seizures
•
drink-alcohol containing beverages during treatment with Methotrexate Injection, or if there are any changes in the amount of alcoholic beverages you drink
•
have fluid in your stomach-area (ascites)
•
have lung problems or fluid in your lungs (pleural effusion)
•
plan to have any surgeries with general anesthesia, including dental surgery
•
have stomach ulcers (peptic ulcer disease)
•
have ulcerative colitis
•
have recently received or are scheduled to receive a vaccine. You should not receive live vaccines during treatment with Methotrexate Injection.
•
are breastfeeding or plan to breastfeed. Methotrexate may pass into your breast milk. Do not breastfeed during treatment and for 1 week after your last dose of Methotrexate Injection.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking certain medicines can affect the amount of methotrexate in your blood and can increase your risk for serious side effects.

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