SKELAXIN® Dosage and Administration

(metaxalone)

2 DOSAGE AND ADMINISTRATION

The recommended dosage of SKELAXIN in adults and pediatric patients 13 years of age and older is 800 mg orally three to four times a day [see Use in Specific Populations (8)].

SKELAXIN (metaxalone) tablets 800 mg are not substitutable on a mg to mg basis with Metaxalone Tablets, 640 mg [see Clinical Pharmacology (12.3)]. When it is appropriate to switch:

Switch only in patients who have been taking Metaxalone Tablets, 640 mg on an empty stomach.
Stop Metaxalone Tablets, 640 mg three times a day and start SKELAXIN 800 mg three times a day on an empty stomach, OR stop Metaxalone Tablets 640 mg four times a day and start SKELAXIN 800 mg four times a day on an empty stomach.

Do not switch from Metaxalone Tablets, 640 mg to SKELAXIN when the patient is taking food during administration.

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Dosage and Administration

2 DOSAGE AND ADMINISTRATION

The recommended dosage of SKELAXIN in adults and pediatric patients 13 years of age and older is 800 mg orally three to four times a day [see Use in Specific Populations (8)].

SKELAXIN (metaxalone) tablets 800 mg are not substitutable on a mg to mg basis with Metaxalone Tablets, 640 mg [see Clinical Pharmacology (12.3)]. When it is appropriate to switch:

Switch only in patients who have been taking Metaxalone Tablets, 640 mg on an empty stomach.
Stop Metaxalone Tablets, 640 mg three times a day and start SKELAXIN 800 mg three times a day on an empty stomach, OR stop Metaxalone Tablets 640 mg four times a day and start SKELAXIN 800 mg four times a day on an empty stomach.

Do not switch from Metaxalone Tablets, 640 mg to SKELAXIN when the patient is taking food during administration.

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